Post-ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar (PEOPLE)

This study assesses the different modalities of post-exposure prophylaxis for leprosy in Madagascar and the Comoros:

  • Identify the selection approach for contacts receiving prophylaxis that is most effective in reducing the incidence of leprosy;
  • Interrupt transmission by asymptomatic persons in the process of developing multibacillary leprosy.


  • Raoul Follereau foundation, Antananarivo
  • National anti-leprosy programme, Madagascar ministry of public health
  • Institute of Tropical Medicine, Antwerp, Belgium
  • AP-HP hospital, France