Public Health

Focus on the illnesses that have the most impact

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Our priority actions are those that have a major impact on public health, such as molecular diagnosis of leprosy, monitoring of paediatric bacterial meningitis and rotavirus, study of the etiology of paediatric diarrhoea, etc.

Monitoring of the sensitivity of Mycobacterium leprae to anti-leprosy treatments

CICM was appointed by the ministry of public health as the national reference laboratory (NRL) for the monitoring of resistance to anti-leprosy treatments in 2017; it diagnoses and studies the resistance of cases of leprosy consulting the dermatology treatment and research centre of JRB university hospital, as well as cases reported in other regions.

Partners

  • Mérieux Foundation, Lyon – France
  • Mycobacteria and Resistance of Mycobacteria to Antituberculosis drugs research centre, Pitié-Salpêtrière university hospital, Paris – France
  • National anti-leprosy programme, ministry of public health – Madagascar
  • Raoul Follereau Foundation – Madagascar

Funding

  • Mérieux Foundation, Lyon – France

Evaluation of the viral load of HIV-1

To verify the efficacy of antiretroviral treatment, the national reference laboratory of the ministry of public health performs HIV viral load tests (HIV VL) but this activity was suspended in 2012. In 2015, CICM set up an open platform to evaluate HIV VL, supported by the Mérieux Foundation.

This activity aims to reinforce laboratory capacities and extend the availability of this analysis to all patients, while also helping to reach the 3rd UNAIDS 90 target in 2020. This activity aims to build the national capacities of the NRL and CICM to perform HIV viral load tests throughout the country. CICM is maintaining the HIV viral load activity until the NRL takes over.

Evaluation of the FilmArray® Meningitis/Encephalitis panel to detect the pathogenic agents of meningitis in hospitalised children under 5 years old (DiaSurMeP)

This is a study of the detection of the etiological agents of meningitis and/or meningoencephalitis in children admitted to the Tsaralalàna mother and child university hospital, using FilmArray®System respiratory/encephalitis panels (donated by the Mérieux Foundation USA). The main goal is to compare the results of bacteria identification obtained by microscope/culture (gold standard) with those of the FilmArray®Meningitis/Encephalitis panel.

Partenaires

  • Tsaralalàna mother and child university hospital – Madagascar
  • Emerging Pathogens Laboratory (EPL), Mérieux Foundation, Lyon – France
Surveillance de la sensibilité de Mycobacterium leprae aux antilépreux